L LongevityGraph
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01 / Overview

One record for
every health input.

LongevityGraph compiles supplements, biomarkers, genetics, wearables, and treatments into a single queryable record. Surfaces what's working, what's conflicting, what's missing.

graph.longevity ~ /ai-session
should I take magnesium with my iron?
⚙ check_interactions
No — separate by 2 hours minimum. Magnesium glycinate cuts iron absorption ~40%. Recommend iron in your fasted AM window; magnesium at bedtime.
CoQ10 with atorvastatin?
⚙ lookup_supplement
Statin depletes CoQ10. Switch ubiquinone → ubiquinol for absorption. SOD2 rs4880 also indicates elevated oxidative stress.
214,300Supplements indexed
200+Genetic variants
28Specialised AI tools
91Treatment presets
02 / Problem

Health data is fragmented by design.

Labs in PDFs. Supplements in screenshots. Genetics in raw 23andMe exports. Nothing connects them — which means nothing catches the conflicts.

Interactions checked 127

Rules cross-checked across your entire stack. Catches conflicts like magnesium blocking iron or statins depleting CoQ10.

Safety dimensions 06

Supplements, drugs, conditions, genetics, dose, and allergens evaluated as one — context generic recommendations don't have.

Genetic variants 200+

SNPs matched to supplement forms. MTHFR carriers taking folic acid instead of methylfolate? Flagged automatically.

03 / Data Layers

Five layers, one record.

Each layer talks to the others. Your supplement stack is checked against your biomarkers, adjusted for your genetics, validated by your wearable trends.

L01 Supplements Brand grading A–F, interaction checking, genetic form matching, timing windows. 27tracked
L02 Biomarkers 200+ markers with condition-adjusted targets, trend analysis, AI-generated insights. 42latest results
L03 Genetics 200+ longevity SNPs analysed. MTHFR, APOE, COMT — connected to supplement forms and disease risk. 200+SNPs
L04 Wearables Oura, WHOOP, Apple Health. Sleep, HRV, resting heart rate synced daily. 68ms HRV
L05 Treatments TRT, peptides, prescriptions. Tracked with compliance, biomarker attribution, monitoring schedules. 91presets
04 / Intelligence

An AI with full record access.

Not a generic chatbot. The model has every biomarker, supplement, variant, and treatment in your record. It calls 28 specialised tools to look up interactions, cross-reference trends, and simulate protocol changes before you make them.

Interaction checks
Biomarker analysis
Protocol simulation
Supplement evaluation
Genetics context
Stack optimization
Trend correlation
Safety monitoring
graph.longevity ~ /tools.run
simulate dropping vitamin D from 5000 IU to 2000 IU
⚙ simulate_protocol
Projected 25-OH-D drop: 62 → 38 ng/mL over 90 days. Below your condition-adjusted target (50). Hold 5000 IU through winter; re-test March.
what's driving my elevated ApoB?
⚙ correlate_trends⚙ genetics_lookup
Three signals: APOE3/4 heterozygote (genetic baseline), saturated fat intake from your diet logs, and CoQ10 form mismatch (ubiquinone, statin-depleted). Statin-CoQ10 axis explains ~30%.
05 / Biological Age

Compute your real age. Track the trajectory.

Computed from 9 published scoring systems using your biomarkers, functional metrics, cognitive performance, and wearable data.

Current bio age −13 yr vs. chrono
44bio
57chrono
020406080
Biological 44 Chronological 57
12-month trajectory −14.0 yr
57 chrono
JanMarJunSepDec
01
9 scoring systems
PhenoAge, GrimAge, DunedinPACE, and more — weighted composite for accuracy.
02
Protocol attribution
See which interventions are aging or protecting each system.
03
Disease risk integration
Five Horsemen risk scoring tied directly to your bio age trajectory.
06 / Inside

Two views: morning summary, supplement check.

The dashboard surfaces the day's deltas. The evaluator scores any supplement before it enters your stack.

Dashboard · daily app.longevitygraph.ai
Supplements 27 +2 this week
Lab markers 42 4 flagged
HRV avg 68 ms +12% MoM
Bio age 44 −13 yr
!
Interaction detected
Magnesium glycinate may reduce iron absorption ~40% if dosed within 2 hours.
Thorne Magnesium Bisglycinate
thorne.com
A
Brand qualityNSF · USP
94
Ingredient matchDSLD verified
88
Safety score1 timing note
76
Genetic fitSLC30A8 favourable
91
!
Timing note
Take 2+ hours apart from iron supplements to prevent absorption interference.
08 / For serious optimizers

Built for people who track 20+ supplements.

Quarterly blood panels. Genetic data on file. A protocol that needs to be defensible. The platform was built for that workload.

Five Horsemen disease risk scoring
Supplement brand grading (A–F)
200+ genetic variant analysis
Peptide pharmacogenomics
Document AI (lab PDFs, DEXA scans)
Causal attribution engine
Stack gap analysis & optimizer
Cognitive assessment battery
Wearable trend integration
Weekly health digest emails
200+
Biomarkers tracked
200+
Genetic SNPs
28
AI tools
91
Treatment presets
09 / Community

What the community is taking.

Anonymized, aggregate data from thousands of optimizers. Most-prevalent supplements, common dosing, brand-grade distribution. illustrative — full data in app

Supplement Prevalence Top brand Grade Dose
01 Vitamin D3 84% Thorne A 5,000 IU
02 Magnesium Glycinate 76% Pure Encapsulations A 400 mg
03 Omega-3 (EPA/DHA) 71% Nordic Naturals A 2 g
04 Creatine Monohydrate 62% Thorne A 5 g
05 CoQ10 (Ubiquinol) 54% Jarrow B 200 mg
06 Taurine 48% NOW Foods B 2 g
07 Glycine 42% BulkSupplements B 3 g
10 / Case study

Bio age 58 → 44 in 12 months.

Illustrative protocol scenario based on the published PhenoAge algorithm. Identifying detail removed.

Subject A-2024-08 · age 57 · 12-month observation Illustrative
58 44yr bio age
−14.0 yr · 9-system composite
01
Full blood panel uploaded
Found 4 out-of-range markers within "normal" reference ranges that the prior physician had not flagged.
02
Stack audit
Identified 3 interactions and 2 incorrect supplement forms for the subject's MTHFR variant. Stack rebuilt with AI guidance.
03
Genetics integrated
APOE4 carrier status identified. Cardiovascular protocol adjusted based on updated risk scoring.
04
12-month trajectory observed
Consistent improvement across the trajectory. Protocol attribution confirmed which interventions drove which deltas.
11 / Pricing

Start free. Upgrade when you're ready.

Full comparison
Free
$0/forever
  • Supplement evaluator
  • Cognitive assessment
  • HRV breathing trainer
  • DSLD lookup (214K products)
  • Interaction checker
Get started
Pro Most popular
$29/month
  • Everything in Free
  • Unlimited biomarker tracking
  • AI health consultant (28 tools)
  • Supplement grading & stack optimizer
  • Genetics analysis (200+ SNPs)
  • Five Horsemen disease risk
  • Biological age scoring
  • Wearable integration
  • Document AI
  • Weekly health digest
Start free trial
12 / Get started

Replace the
spreadsheet.

Connect your data. Verify your protocol. Track outcomes.

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