01 / BlogHealth optimization
Health optimization
deep dives.
Supplement science, biomarker interpretation, and how the platform works under the hood.
Mar 26, 2026
How Our 6-Dimension Safety Engine Works
Most supplement interaction checkers look at one thing. Ours checks six dimensions simultaneously — contraindications, drug interactions, supplement-supplement interactions, dose/total daily load, condition interactions, and allergen safety.
· safety· engineering
3 min
Mar 25, 2026What Is PhenoAge and How to Calculate Yours
PhenoAge uses 9 routine blood biomarkers to estimate your biological age. Here's how the algorithm works, what the numbers mean, and how to improve your score.
· biomarkers· science
2 min
Mar 24, 2026How We Grade Supplement Brands A Through F
Our brand quality scoring system evaluates 35+ attributes across certifications, manufacturing practices, testing transparency, and FDA compliance. Here's the methodology.
· supplements· methodology
3 min
Mar 23, 2026200+ Genetic Variants We Analyze — and Why They Matter
From MTHFR to APOE to COMT — which genetic variants LongevityGraph analyzes, how they affect your supplement protocol, and what to do about them. Over 200 variants across 15 categories.
· genetics· science
2 min
Mar 22, 20265 Supplement Interactions Most People Miss
These aren't the obvious ones. Five supplement interactions that slip through generic checkers — and why context matters more than a simple yes/no answer.
· safety· supplements
3 min